ICAP

United States

United States

While ICAP is renowned for its work supporting health in countries around the world, it also carries out vital initiatives in New York City that serve key communities and inform new approaches to global health.

From its headquarters at the Mailman School of Public Health, which is part of the Columbia University Irving Medical Center, ICAP draws on world-class resources and expertise to conduct research and design programs that transforms the health of people worldwide.

ICAP’s two research centers in New York City, the Bronx Prevention Center and the Harlem Prevention Center, carry out cutting-edge biomedical and public health investigations in areas that have been historically underserved and disproportionately impacted by HIV and, more recently, COVID-19 and mpox. ICAP works with local community-based organizations, religious leaders, and advocates to promote community awareness of and engagement with the research studies.

Through Columbia University, ICAP also supports additional COVID-19 surveys and various student fellowship programs, engaging students to participate in the design, implementation, and evaluation of ICAP-supported programs while working side-by-side with its experts.

Projects 

HPTN 115/ATN 173 (foXXy doxy)

  • current: Harlem
Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Among Adolescent and Young People Assigned Female at Birth in the United States HPTN 115/Foxxy Doxy looks at doxycycline, a well-known antibiotic that is commonly used to prevent and treat acne and some sexually transmitted infections (STIs) like gonorrhea, chlamydia, and syphilis, to learn if taking doxycycline ...

PURPOSE 3/HPTN 102

  • current: Harlem
A Phase 2, open-label, multicenter, randomized study to evaluate the pharmacokinetics, safety, and acceptability of twice-yearly long-acting subcutaneous lenacapavir for pre-exposure prophylaxis in cisgender women in the United States ...

PURPOSE 3/HPTN 102

  • current: Bronx
A Phase 2, open-label, multicenter, randomized study to evaluate   lenacapavir, a medication given as twice-yearly long-acting shots versus the standard oral medication (tenofovir/emtricitabine) used for prevention of HIV in cisgender women in the United States. The study is fully enrolled and nearing the end of the randomized phase.  During this study, lenacapavir received FDA approval ...

PURPOSE 365

  • current: United States, Bronx
A study of a new formulation of lenacapavir that is designed to be used as a once-yearly intramuscular shot for prevention of HIV from sex. This multicenter study is fully enrolled and in follow up. ...

PURPOSE 4/HPTN 103

  • current: Bronx
A Phase 2, open-label, multicenter, randomized study to evaluate lenacapavir, a medication given as twice-yearly long-acting shots versus standard daily oral pills (tenofovir/emtricitabine) for prevention of HIV among people who are at risk for HIV via injection drug use. The study is fully enrolled and nearing the end of the randomized phase. ...

Clinical Trials

ICAP at Columbia University Clinical Trials Unit (ICAP CTU)

An innovative and comprehensive approach to HIV prevention and therapeutic research.

The ICAP CTU aims to support the design and implementation of research to address gaps in the global HIV response, including through clinical research sites in Harlem, Bronx, and Eswatini. Led by Wafaa El-Sadr, MD, MPH, MPA, and Jessica Justman, MD, this work is carried out through the ICAP at Columbia University Clinical Trials Unit (CTU). 

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ICAP in the United States

Active Years

2003 to present

Key Technical Areas
  • Clinical Research and Trials
  • COVID-19 Research
  • PrEP Research
  • Surveys
  • Sexually Transmitted Infections Research
Current Funders
  • The Rockefeller Foundation
  • The Samuels Foundation
  • The New York Community Trust

 

 

ICAP Founder and Global Director

Wafaa El-Sadr, MD, MPH, MPA

Dr. Wafaa El-Sadr is the founder and director of ICAP and an international expert in epidemiology and research on the prevention and management of HIV, tuberculosis, and other infectious diseases. She is also the director of Columbia World Projects. For over three decades, she has advocated for families and communities most impacted by HIV and championed a collaborative, multidisciplinary approach to confronting the global epidemic.

Based at Columbia University, she leads ICAP’s portfolio of projects in 30 countries and manages a global team of over 2,000 staff. Under her leadership, ICAP has become a global leader in HIV and health systems strengthening. She is also the director of the Mailman School’s Global Health Initiative (GHI), which mobilizes the University community to address critical challenges in global health.

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The New York City Preparedness & Recovery Institute (PRI)

Prepare.Recover.Invest

PRI is a landmark initiative designed to help prepare NYC for future public health threats – from infectious diseases to climate-related health emergencies – by fortifying and diversifying the city’s public health infrastructure, improving health equity, and elevating NYC as a model of public health preparedness across the globe.

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Jobs in the United States

For ICAP positions in this country, visit ICAP's international jobs page.

To search all job listings, see the ICAP careers page