Funded by CDC emergency ITF funds, ICAP has launched an Infection Prevention and Control (IPC) Community of Practice in East Africa to respond to the COVID-19 pandemic. Through building a robust south-to-south learning network the next twenty-seven months, the project seeks to enhance the capacity of hospital-based IPC Focal Points to support compliance with IPC standards in facilities across Uganda, Kenya, Tanzania, and Ethiopia. The IPC Community of Practice will include rapid training on COVID-19-related IPC, skills building and mentorship, and supportive supervision for IPC QI projects.