From October 2011 to March 2017, with PEPFAR funding through the Centers for Disease Control and Prevention (CDC), ICAP provided intensive technical assistance and logistical support to 192 health facilities in four regions of Côte d’Ivoire (Worodougou-Béré, Lôh-Djiboua, Agnéby-Tiassa-Mé, and Abidjan 2) and two tertiary care facilities in Abidjan city (Cocody University Teaching Hospital and the Pasteur Institute of Côte d’Ivoire). ICAP support under the project measurably increased uptake and quality of HIV prevention, care, and treatment services—gains that were achieved through a dynamic partnership with the Ministry of Health, capacity strengthening of decentralized health management teams and multidisciplinary teams of health care workers, and direct engagement of people living with HIV in the design and implementation of health services.