Journal Club
March/April 2019: BRIEF TB/A5279 Study suggests 1-month rifapentine/isoniazid regimen prevents TB in people living with HIV as well as standard 9-month isoniazid alone
Article and Study Summary One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis. Published in: N Engl J Med. 2019;380 (11):1001-1011. https://doi.org/10.1056/NEJMoa1806808. Authors: Swindells S, Ramchandani R, Gupta A, et al for the BRIEF...
February 2019: HPTN 071 (PopART) results show community-based distribution of HIV self-testing kits increases knowledge of HIV status, especially among men
Article and Study Summary Community based distribution of oral HIV self-testing kits in Zambia: a cluster-randomised trial nested in four HPTN 071 (PopART) intervention communities. Published in: Lancet HIV. 2019;6(2):e81–e92. DOI: 10.1016/S2352-3018(18)30258-3...
January 2019: When starting ART in adults with advanced HIV disease and TB coinfection, prophylactic prednisone reduces risk of paradoxical TB-associated IRIS
Article and Study Summary Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS. Published in: N Engl J Med. 2018; 379:1915-1925. DOI: 10.1056/NEJMoa1800762 Authors: Meintjes G, Stek C, Blumenthal L, et al. Summary: This article reports on a...