Maternal Perinatal HIV Infection is Associated with Increased Infectious Morbidity in HIV-Exposed Uninfected Infants

Powis KM, Slogrove AL, Okorafor I, Millen L, Posada R, Childs J, Abrams EJ, Sperling RS, Jao J.
Pediatr Infect Dis J. 2018 Nov 16. doi: 10.1097/INF.0000000000002253. [Epub ahead of print]

Abstract

More women with perinatally-acquired HIV are giving birth. We evaluated infectious cause hospitalizations (ICH) in HIV-uninfected infants of perinatally HIV-infected (HEU-P), non-perinatally HIV-infected (HEU-N), and HIV-uninfected women (HUU) through 12 months-of-life at an urban tertiary heath center. HEU-P infants experienced higher ICH risk compared to HEU-N and HUU infants. Identification of biological and structural drivers of differences are needed.

Maternal Perinatal HIV Infection is Associated with Increased Infectious Morbidity in HIV-Exposed Uninfected Infants

Abstract

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