Recognizing that health workers were lacking specific training on how to successfully engage HIV-infected adolescents in HIV care and treatment, Zambia’s Ministry of Health requested that ICAP lead the development of a curriculum focused on the provision of youth-friendly HIV services. Building on lessons learned delivering HIV care and treatment to adolescents, ICAP collaborated with the University Teaching Hospital and the University of Medicine and Dentistry of New Jersey – Francois Xavier Bagnoud Center to design a national standardized curriculum that would empower multidisciplinary health workers to have the confidence and skills to provide comprehensive, youth-friendly HIV services that support adolescents’ health development, psychosocial well-being, retention, adherence, sexual reproductive health, and eventual transition to adult HIVservices. The curriculum, which complements the national pediatric ART training, was finalized in 2011 and was subsequently implemented nationally. The training curriculum includes a 15-module Trainer Manual, a Participant Manual, and accompanying PowerPoint slides.