The HIV Prevention Trials Network (HPTN) announced results from HPTN 083, a global randomized, controlled, double-blind study that compared the safety and efficacy of long-acting injectable cabotegravir (CAB LA) to daily oral tenofovir/emtricitabine (TDF/FTC) (Truvada) for pre-exposure prophylaxis (PrEP). The study showed that CAB LA lowered HIV incidence among cisgender men and transgender women who have sex with men.

“The findings from HPTN 083 are an important milestone along the path towards ending the HIV epidemic,” said Wafaa El-Sadr, MD, MPH, HPTN co-principal investigator, director of ICAP and professor of epidemiology and medicine at Columbia University in New York. “We look forward to the results from HPTN 084, a critically important sister study among women at risk for HIV in sub-Saharan Africa.”

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