HPTN 071 (PopART) examined the impact of a package of HIV prevention interventions, including universal testing and treatment, on community-level HIV incidence amongst more than one million people living in 21 urban and peri-urban communities in Zambia and South Africa. Primary results were published in The New England Journal of Medicine on 18 July 2019 and showed delivery of an HIV prevention package that included offering in-home HIV testing to all household members, with immediate referral to HIV care and treatment for all people living with HIV, can substantially reduce new HIV transmissions.

“Modelling the HPTN 071 (PopART) effects into the future provides evidence that achieving high coverage with HIV testing and treatment can be part of a pathway towards achieving epidemic control,” said Dr. Wafaa El-Sadr, HPTN co-principal investigator and professor of epidemiology and medicine at Columbia University, New York. “Many implementation insights can be gained from the study on how to accomplish the scale-up of these interventions.”

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Read the full PopART study in the New England Journal of Medicine