ICAP conducted an innovative, mixed-methods, cluster-randomized implementation science study that aimed to evaluate the effectiveness and acceptability of a combination community-based intervention versus the standard of care to identify and screen child contacts of adult TB cases in Berea District, Lesotho, and provide those eligible with Isoniazid Preventive Therapy. This study leveraged ICAP’s partnership with the Lesotho MOH and holistically addresses the complex provider-, patient-, and caregiver-related barriers to prevention of childhood TB through: nurse training and mentorship; health education for caregivers and patients by village health workers; adherence support using text messaging and village health workers; and multidisciplinary team meetings.
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