In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products

This study investigated the experimental microbicide gel tenofovir to protect women against HIV. The study provided information on how much vaginal tenofovir gel, when used in combination with common vaginal products, will interfere with the local and or systemic exposure of the tenofovir, and vice versa, to optimize effectiveness as an HIV prevention tool. (funded by CONRAD) Schwartz, J., Justman, J., et al. 2016. In Vivo Drug-drug Interactions Between Tenofovir Gel and Three Commonly Used Vaginal Products. AIDS Research and Human Retroviruses, 32, 353-353. Web Links: https://clinicaltrials.gov/ct2/show/NCT01813162